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Early Fluid Resuscitation in Severe Trauma

It's been a fantastic (and busy) day at the EDTCC headquarters.  A mammoth whiteboard session with EDExam's very own Andy Buck, on a collaborative upcoming project (more to follow), followed by a podcast on Minh Le Cong's (@rfdsdocPHARM blog with some of Oz ED's greats - Casey Parker (@broomedocs) of Broomedocs blog, and the vivacious Michelle Johnston (@Eleytherius) from LITFL blog.

Listen to the podcast here.

This podcast was stimulated by a great review article in the BMJ by Tim Harris and Karim Brohi (@karimbrohi) at the Royal London Hospital.

In this article, the key concepts of damage control resuscitation, and fluid resucitation in different settings are explored and outlined. I highly recommend that you get access to the full article. 

"Summary points

  • Critically injured trauma patients may have normal cardiovascular and respiratory parameters (pulse, blood pressure, respiratory rate), and no single physiological or metabolic factor accurately identifies all patients in this group

  • Initial resuscitation for severely injured patients is based on a strategy of permissive hypovolaemia (hypotension) (that is, fluid resuscitation delivered to increase blood pressure without reaching normotension, aiming for cerebration in the awake patient, or 70-80 mm Hg in penetrating trauma and 90 mm Hg in blunt trauma) and blood product based resuscitation

  • This period of hypovolaemia (hypotension) should be kept to a minimum, with rapid transfer to the operating theatre for definitive care

  • Crystalloid or colloid based resuscitation in severely injured patients is associated with worse outcome

  • Once haemostasis has been achieved, resuscitation targeted to measures of cardiac output or oxygen delivery or use improves outcome

  • Tranexamic acid administered intravenously within 3 h of injury improves mortality in patients who are thought to be bleeding"

BMJ 2012; 345 doi: 10.1136/bmj.e5752 (Published 11 September 2012)



Karim Brohi's (@karimbrohilecture on Permissive Hypotension

Broome Docs Massive Transfusion Protocol 

PHARM Podcast 39 - Haemorrhagic shock in remote settings with the Three Resusciteers

EMCrit Blog - Tranexamic Acid (TXA), Crash 2 with Tim Coats.

EMCrit Blog - Podcast 30 - Haemorrhagic Shock Resuscitation with Richard Dutton MD

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    seendLcM Xanax
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    EDTCC - Blog Archive - Early Fluid Resuscitation in Severe Trauma
  • Response
    I find it hard to believe that its safe to listen to you. I just read the preliminary report about the inquiry into why people were infected with hepatitis C and HIV from contaminated blood and blood products. Hundreds of people in Scotland, including haemophilia sufferers and other patients, were given ...
  • Response
    It is the coolest site, keep so!
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    There are some interesting points in time in this article but I dont know if I see all of them heart to eye . There is some validity but I will hold opinion until I look into it further. Good clause, thanks and we want more! Added to FeedBurner likewise.

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